2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine - Names and Identifiers
Name | 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine
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Synonyms | 7-Azaindoline 7-azaindoline 2,3-Dihydro-7-azaindole 1H,2H,3H-pyrrolo[2,3-b]pyridine 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine 2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE 1H-Pyrrolo[2,3-b]pyridine, 2,3-dihydro- 1H-Pyrrolo[2,3-b]pyridine,2,3-dihydro-(6CI,8CI,9CI) 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine 7-azaindoline
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CAS | 10592-27-5
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InChI | InChI=1/C7H8N2/c1-2-6-3-5-9-7(6)8-4-1/h1-2,4H,3,5H2,(H,8,9) |
2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine - Physico-chemical Properties
Molecular Formula | C7H8N2
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Molar Mass | 120.15 |
Density | 1.23 |
Melting Point | 78-83 °C |
Boling Point | 114°C/10mmHg(lit.) |
Flash Point | 114.012°C |
Water Solubility | Slightly soluble in water. |
Solubility | soluble in Methanol |
Vapor Presure | 0.009mmHg at 25°C |
Appearance | White to light brown powder |
Color | White |
Maximum wavelength(λmax) | ['306nm(Cyclohexane)(lit.)'] |
pKa | 10.75±0.20(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.568 |
MDL | MFCD06659751 |
2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine - Risk and Safety
Hazard Symbols | Xn - Harmful
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Risk Codes | R22 - Harmful if swallowed
R36 - Irritating to the eyes
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Safety Description | 36 - Wear suitable protective clothing.
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WGK Germany | 3 |
HS Code | 29339900 |
Hazard Class | IRRITANT |
2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine - Introduction
Dihydro-7-azaindole, also known as indoline or indoline, is an organic compound with the chemical formula C8H9N. Its appearance is white or light yellow solid with special nitrogen heterocyclic structure. The following is a description of the properties, uses, preparation and safety information of dihydro-7-azaindole:
Nature:
-Dihydro-7-azaindole is a hydrophobic substance, insoluble in water, but soluble in organic solvents such as ethanol, ether, etc.
-It is stable at room temperature, but it is easy to decompose under high temperature or electrostatic conditions.
-Dihydro-7-azaindole is a white or pale yellow solid that is not susceptible to oxidation in air.
Use:
-Dihydro-7-azaindole is an important organic synthesis intermediate, commonly used in the preparation of indole compounds.
-It can be used as raw materials for applications such as dyes, fluorescent probes and photosensitizers.
Preparation Method:
There are many methods for the synthesis of-dihydro-7-azaindole, one of which is commonly used to prepare by reacting indole with ammonia.
-Indole and ammonia under appropriate reaction conditions, through oxidation and cleavage reaction to produce dihydro-7-azaindole.
Safety Information:
-Dihydro-7-azaindole has no obvious acute toxicity to the human body under normal use conditions.
-However, it is still recommended to wear protective gloves and safety glasses during use to prevent direct contact and inhalation.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-During storage and handling, care should be taken to avoid contact with oxidants and combustibles to avoid danger.
-If waste needs to be disposed of, it should be disposed of correctly in accordance with local regulations.
Last Update:2024-04-10 22:29:15